Although there is little research on sucralfate and pregnancy, the drug is considered a pregnancy Category B drug by the Food and Drug Administration. Its safety during pregnancy is not established, but studies performed in animals have not shown that it causes harm to fetuses. However, animal studies may not be fully representative of human response, so care should be exercised when administering this medication to expectant women. Moreover, sucralfate is not known to be excreted in breast milk. However, many other drugs are excreted in human breast milk, so it should be administered with caution during pregnancy and nursing.
When used to treat gastric ulcers, sucralfate acts as a physical barrier between the ulcer and the gastric mucosa. It is believed to work by inactivating pepsin and adsorbing bile acids. It is also thought to be cytoprotective, since it stimulates the synthesis of prostaglandins. It does not significantly affect gastric acid output, although it can slow gastric emptying.
Sucralfate is taken by mouth, usually two to four times daily. It is best taken on an empty stomach, at least one hour before a meal. The tablets should be crushed to aid in absorption. Sucralfate should never be injected through a needle. The recommended dosage depends on the medical condition of the patient.
In addition to its anti-inflammatory and pain-relieving properties, sucralfate also reduces the absorption of many drugs. Therefore, it is important to consult your pharmacist for additional information about the drug. In addition, you can contact the Food and Drug Administration (FDA) for further information regarding sucralfate and other medications.
It is important to remember that sucralfate should be taken on a regular basis and at the same times each day. It should not be stopped even if the ulcer pain stops. In addition, some medications may not be effective when taken at the same time as sucralfate, so it is best to consult your pharmacist on what time to take them.
Patients with chronic kidney failure should be careful when using sucralfate. Although sucralfate is well tolerated, aluminum accumulation in the kidneys can occur in patients with chronic kidney disease. If you are on dialysis, you may want to consult your doctor about suralfate. It is also safe for diabetics but should be used with caution for those with impaired kidney function.
In addition to being a safe medication for treating ulcers, sucralfate is also used to protect against ulcers. It forms a barrier over the ulcer to shield it from stomach acid. It is available in suspension and tablet forms. It was first approved by the FDA in 1982. A doctor’s prescription is required to use sucralfate.
Sucralfate belongs to a class of drugs called gastroduodenal cytoprotective agents. It is used for the prevention and treatment of duodenal ulcers. It can also be used to prevent stress ulcers in critically ill patients. It forms a coating over the ulcer, protecting it from acid and allowing it to heal.
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